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Overall, we found no significant difference in https://www.nikesneakersaustralia.nu the incidence of a serious vascular event between participants allocated to a selective COX 2 inhibitor and those allocated to a traditional NSAID 340 vascular events during 33 260 person years of exposure to a selective COX 2 air force white nike
inhibitor (1.0%/year) versus 211 vascular events during 23 325 person years with a traditional NSAID (0.9%/year) (rate ratio 1.16, 0.97 to 1.38; P = 0.1) (fig 3). However, we found marked heterogeneity between the rate ratios for vascular events in trials comparing a selective COX 2 inhibitor with naproxen and those comparing a selective COX 2 inhibitor with a non naproxen NSAID (2 = 10.2, df = 1; P = 0.001). We found similar heterogeneity for myocardial infarction (2 = 4.3, df = 1; P = 0.04), stroke (2 = 3.6, df = 1; P = 0.06), and vascular death (2 = 5.3, df = 1 P = 0.02).
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